IBUPROFEN TABLET 400mg

Indications:

For the relief of pain of non-serious arthritic conditions and for the relief of rheumatic or muscular pain, backache, neuralgia, headache including migraine headache, dental pain, dysmenorrhoea, feverishness and the symptoms of colds and influenza.

Dosage and Administration:

For oral administration and short-term use only.

Adults, the elderly and children over 12 years:

Undesirable effects may be minimised by using the lowest effective dose for the shortest duration necessary to control symptoms . The patient should consult a doctor if symptoms persist or worsen, or if the product is required for more than 10 days.

One tablet to be taken up to three times a day, as required.

Leave at least four hours between doses and do not take more than 3 tablets (1200mg) in any 24 hour period.

Adolescents (12-18 years old):

If this medicinal product is required for more than 3 days, or if symptoms worsen a doctor should be consulted.

Children under 12 years:

Not suitable for children under 12 years.

Precautions & Warning:

Do not take if you:

have (or have had two or more episodes of) a stomach ulcer, perforation or bleeding

are allergic to ibuprofen or any other ingredient of the product, aspirin or other related painkillers

are taking other NSAID painkillers, or aspirin with a daily dose above 75 mg

Speak to a pharmacist or your doctor before taking if you:

have or have had asthma, diabetes, high cholesterol, high blood pressure, a stroke, heart, liver, kidney or bowel problems

are a smoker

are pregnant

If symptoms persist or worsen, consult your doctor.

Contra-indications:

Hypersensitivity to ibuprofen or any of the excipients in the product.

Patients who have previously shown hypersensitivity reactions (e.g. asthma, rhinitis, angioedema or urticaria), in response to ibuprofen, aspirin or other non-steroidal anti-inflammatory drugs.

Active or history of recurrent peptic ulcer/haemorrhage (two or more distinct episodes of proven ulceration or bleeding).

History of gastrointestinal bleeding or perforation, related to previous NSAIDs therapy.

Severe heart failure (NYHA Class IV), renal failure or hepatic failure

Third trimester of pregnancy

Children under 12 years.

Drug interactions:

Ibuprofen should be avoided in combination with:

Acetylsalicylic acid: Unless low-dose aspirin (not above 75mg daily) has been advised by a doctor. Concomitant administration of ibuprofen and acetylsalicylic acid is not generally recommended because of the potential of increased adverse effects.

Ibuprofen should be used with caution in combination with:

Anticoagulants, Antihypertensives and diuretics, Corticosteroids, Anti-platelet agents and selective serotonin reuptake inhibitors (SSRIs), Cardiac glycosides, Lithium, Methotrexate , Ciclosporin, Mifepristone, Tacrolimus, Zidovudine, Quinolone antibiotics

Storage instructions:

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing and out of the reach of children.